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Dose-by-dose weight loss in Phase 2 (NEJM) Phase 2 NEJM weight loss by dose, 24 and 48 weeks Dose 1 mg 24 weeks -7.2% 48 weeks -8.7% Dose 4 mg 24 weeks -12.9% 48 weeks -17.5% Dose 8 mg 24 weeks -15.7% 48 weeks -22.8% Dose 12 mg 24 weeks -17.5% 48 weeks -24.2% Dose Placebo 24 weeks -1.6% 48 weeks -2.1% Source: Jastreboff et al., NEJM 2023

Feeling exhausted or foggy, even with enough sleep

The combination can affect all of these, and catching abnormalities early prevents complications

And we have a gene that's able to make heterocyclic amines, to basically detoxify it so it's not as harmful

The conversion question, "20 units is how many mg," almost always applies to people using compounded semaglutide from multi-dose vials with insulin syringes